According to a history fact sheet released by Davis-Monthan Air Force Base:
D-M became a military base in 1925, but its origins can be traced to the earliest days of civil aviation. In 1927, Charles Lindbergh, fresh from his non-stop crossing of the Atlantic Ocean, flew his "Spirit of St. Louis" to Tucson to dedicate Davis-Monthan Field -- then the largest municipal airport in the United States.
The base was named in honor of Lieutenants Samuel H. Davis and Oscar Monthan, two Tucsonans and World War I era pilots who died in separate military aircraft accidents.
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